Wolf AJ, Reyes CN, Liang W, Becker C, Shimada K, Wheeler ML, Cho HC, Popescu NI, Coggeshall KM, Arditi M, Underhill DM. Hexokinase is an innate immune receptor for the detection of bacterial peptidoglycan. Cell. 2016 Jul 28;166(3):624-636. http://www.cell.com/cell/fulltext/S0092-8674(16)30723-1.
Ma J, Becker C, Reyes C, Underhill DM. Cutting edge: FYCO1 recruitment to dectin-1 phagosomes is accelerated by light chain 3 protein and regulates phagosome maturation and reactive oxygen production. J Immunol. 2014 Feb 15;192(4):1356-1360. http://www.jimmunol.org/content/192/4/1356.
Iliev ID, Funari VA, Taylor KD, Nguyen Q, Reyes CN, Strom SP, Brown J, Becker CA, Fleshner PR, Dubinsky M, Rotter JI, Wang HL, McGovern DPB, Brown GD, Underhill DM. Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis. Science. 2012;336(6086):1314-1317. http://www.sciencemag.org/content/336/6086/1314.
Kaplan A, Ma J, Kyme P, Wolf AJ, Becker CA, Tseng CW, Liu GY, Underhill DM. Failure to induce interferon-beta production during Staphylococcus aureus infection contributes to pathogenicity. J Immunol. 2012;189(9):4537-4545. http://www.jimmunol.org/content/189/9/4537.full.
Ma J, Becker C, Lowell CA, Underhill DM. Dectin-1-triggered recruitment of light chain 3 protein to phagosomes facilitates major histocompatibility complex class II presentation of fungal-derived antigens. J Biol Chem. 2012 Oct 5;287(41):34149-34156. http://www.jbc.org/content/287/41/34149.
Shimada T, Park B, Wolf AJ, Brikos C, Goodridge HS, Becker CA, Reyes CN, Miao EA, Aderem A, Götz F, Liu GY, Underhill DM. Staphylococcus aureus evades the lysozyme-based digestion of peptidoglycan that links phagocytosis and macrophage IL-1 secretion. Cell Host and Microbe. 2010;7(1):38-49. http://www.cell.com/cell-host-microbe/abstract/S1931-3128(09)00418-1.
Contact the Underhill Lab
8700 Beverly Blvd. Davis Building, Room 4094F Los Angeles, CA 90048