Research in the Martins Laboratory focuses on the molecular regulation of immune responses, particularly the mechanisms regulating immune cell function in nonlymphoid tissues. We are interested in identifying pathways that can be harnessed to manipulate immune cell function, and potentially interfere with ongoing immune responses associated with chronic inflammatory conditions.
The Martins Laboratory is affiliated with the F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute and the Department of Medicine.
- Role of the transcriptional regulator Blimp1 in controlling effector and regulatory T cell at the intestinal mucosa.
- Shaping of the intestinal commensal microbiota by T cells.
- Blimp1’s role in tissue-resident myeloid cells.
- The requirements for the development of protective T cell responses against Staphylococcus aureus.
- Regulation of T cell function by the intestinal commensal microbiota.
- Department of Medicine, Division of Gastroenterology
- F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute (IBIRI)
- Department of Biomedical Sciences
- Research Division of Immunology
Meet Our Team
Learn more about the scientists, faculty members, investigators and other healthcare professionals of the Martins Laboratory, whose dedicated efforts lead to groundbreaking discoveries.
Yao C, Bora SA, Parimon T, Zaman T, Friedman OA, Palatinus JA, Martins GA, Surapaneni NS, Matusov YP, Cerro Chiang G, et al.
Cell Rep. 2021 Jan 5;34(1):108590.
Benevides L, Costa RS, Tavares LA, Russo M, Martins GA, da Silva LLP, Arruda LK, Cunha FQ, Carregaro V, Silva JS.
J Allergy Clin Immunol. 2019 Mar;143(3):1119-1130.e3.
Ogawa C, Bankoti R, Nguyen T, Hassanzadeh-Kiabi N, Nadeau S, Porritt RA, Couse M, Fan X, Dhall D, Eberl G, Ohnmacht C, Martins GA.
Cell Rep. 2018 Oct 2;25(1):19-28.e5.
Contact the Martins Lab
110 N. George Burns Road
Davis Building, Room 4094C
Los Angeles, CA 90048