My lab's research focuses on two areas: innate immunity and myelopoiesis. During my training at the University of Glasgow, U.K., and at Cedars-Sinai, I gained research experience in innate immunity, in particular microbial detection by pattern recognition receptors expressed by myeloid cells (neutrophils, monocytes, macrophages and dendritic cells). I subsequently developed an interest in the production of these cells by hematopoietic stem and progenitor cells (myelopoiesis), and in 2010 joined the Board of Governors Regenerative Medicine Institute at Cedars-Sinai to start my independent lab.
The Goodridge Laboratory studies include pathways and mechanisms of myelopoiesis during homeostasis and in response to infections and tumors. My lab also has interests in the roles of hematopoietic cells in tissue aging and neurodegenerative disease, as well as the use of induced pluripotent stem cell-derived myeloid cells to study and treat human disease.
I am a professor at Cedars-Sinai and an adjunct professor in the David Geffen School of Medicine at UCLA. I currently serve as co-director of the immunology, infection and inflammation core course in the Cedars-Sinai PhD Program in biomedical and translational sciences and was previously founding director of the Cedars-Sinai Postdoctoral Scientist Program.