Researchers are collaborating with UCLA and Cedars-Sinai infectious disease specialists in a project by the UCLA Clinical and Translational Science Institute, UCLA AIDS Institute and the UCLA Center for AIDS Research to study the effects of HIV and hepatitis C treatment on endothelial function in men and women.
Investigators are also collaborating with the Texas Heart Institute to determine if women who stop their menstrual cycle due to low estrogen levels as a result of stress, over-exercising or weight loss have worse blood vessel function than women with regular monthly menstrual cycles.
Collaborating with the Harvard School of Public Health and Mongolian health officials, Cedars-Sinai investigators are studying pregnant women with preeclampsia to determine if it causes ischemic heart disease (IHD). Mongolia has a high rate of preeclampsia, which gives researchers a large patient population to study. Vascular endothelial dysfunction has been implicated in the cause of both preeclampsia and cardiovascular disease, but questions remain as to whether vascular dysfunction leading to preeclampsia occurs at the time of pregnancy or prior to pregnancy.
Researchers also collaborate with the Harvard Medical School to determine whether the dose, formulation or route of delivery of menopause hormone therapy changes the risk of IHD.