OnCore & Clinical Trial Informatics

The Clinical Research Office provides informatics support for protocol activation, tracking, accrual monitoring, and database development.  In addition, through collaboration with the Research Informatics and Scientific Computing Core (RISCC) custom databases and tools can be developed to support clinical research efforts.  

Cedars-Sinai Cancer utilizes the OnCore™ clinical trial management system (CTMS) to track our portfolio of cancer clinical trials. OnCore™ is a secure web-based system licensed from Forte Research Systems®. The system is housed at the Medical Center's secure Data Center and is compliant with applicable laws and regulations.

OnCore provides for the efficient and secure organization of data in a centralized repository so that trials can run more smoothly. Automated tools within OnCore and ongoing integration efforts with the institutional electronic medical record (CS Link) and IRB system (CS-IRB) provide consistency, compliance, and provide the user with access to protocol details and subject information in a timely manner.

OnCore empowers the research community by providing a systematic way of tracking, accessing, monitoring and reporting on overall clinical trial activity and productivity.

Access to OnCore is granted through the Cedars-Sinai Service Center. Personalized training for OnCore is available by contacting groupsoccicroadmin@cshs.org. System documentation, manuals and work instructions can be accessed at the CRO Sharepoint site.

Below are basic components part of OnCore CTMS.

REDCap is a robust, secure web application for building and managing data for research studies developed and managed by Vanderbilt University and hosted by Cedars Sinai. Our highly qualified research staff are trained to develop a case report (CRF) and other forms within the system to support investigator-initiated research projects. Our team of experts works with investigators, statisticians, and other key stakeholders to create and maintain study-specific e-CRFs that are compliant with HIPAA and 21CRF Part 11. Access to REDCap is granted through the Cedars-Sinai Service Center.

The research informatics core is a shared resource at Cedars Sinai who provides a wide variety of services including software and web-based applications to facilitate cancer research. The clinical research informatics core work with RISC to create applications that support investigator initiated research and clinical research operations.